Small Interfering RNA (siRNA)
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Small Interfering RNA (siRNA) Inhibitors
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Small Interfering RNA (siRNA) Pre-designed Sets
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Small Interfering RNA (siRNA) Control
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Small Interfering RNA (siRNA) Related Products (29612)
Related Products (29612)
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Zerlasiran sodium
0 ImagesCat. No.: HY-147425ASynonyms: SLN360 sodiumZerlasiran (SLN360) sodium is a siRNA targeting apolipoprotein A (ApoA). Zerlasiran sodium targets hepatic ApoA synthesis via RNA interference to degrade encoding mRNA. Zerlasiran sodium can be used for the research of atherosclerotic cardiovascular disease and elevated ApoA levels.
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Elebsiran sodium
0 ImagesCat. No.: HY-147266Synonyms: VIR-2218 sodiumElebsiran (VIR-2218) sodium is a siRNA that targets and degrades hepatitis B virus (HBV) and hepatitis D virus (HDV) RNA transcripts. Elebsiran sodium leads to a significant decrease in HBV surface antigen (HBsAg) and a reduction in viral load. Elebsiran sodium binds to the sialic acid-depleted glycoprotein receptor (ASGPR) on the surface of liver cells through the GalNAc ligand, achieving liver-targeted delivery and demonstrating improved liver safety. Elebsiran sodium can be used for the study of chronic HBV/HDV infections.
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Revusiran sodium
0 ImagesCat. No.: HY-132590ASynonyms: ALN-TTRSC sodiumRevusiran (ALN-TTRSC) sodium is an RNA interference agent targeting the mRNA of transthyretin (Transthyretin, TTR). Revusiran sodium mediates sequence-specific degradation of TTR mRNA through RNA interference, reduces the synthesis of TTR protein, binds to GalNAc ligands, and is taken up by hepatocytes via the asialoglycoprotein receptor. Revusiran sodium exhibits favorable nonclinical safety profiles. Revusiran sodium can be used in studies related to transthyretin-mediated amyloidosis.
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HIF1A Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS06168HIF1A Human Pre-designed siRNA Set A contains three designed siRNAs for HIF1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SPP1 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS13702SPP1 Human Pre-designed siRNA Set A contains three designed siRNAs for SPP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Olpasiran sodium
0 ImagesCat. No.: HY-153492APurity: 98.82%Synonyms: AMG 890 sodium; ARC-LPA sodiumOlpasiran (AMG 890, ARC-LPA) sodium is an N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted siRNA. Olpasiran sodium directly inhibits LPA messenger RNA translation in hepatocytes and potently reduce Lp(a) concentration. Olpasiran sodium can be used for the research of cardiovascular disease, such as atherosclerosis.
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Cemdisiran
0 ImagesSynonyms: ALN-CC5Cemdisiran (ALN-CC5) is an N-acetylgalactosamine-conjugated RNAi agent and also a complement component C5 inhibitor. Cemdisiran targets C5 mRNA, cleaves C5 mRNA via the endogenous RNA interference pathway, and inhibits the production of C5 protein in the liver. Cemdisiran exerts a dose-dependent inhibitory effect on total C5 concentrations in cynomolgus monkeys. When used in combination with Pozelimab (HY-P99786) in cynomolgus monkeys, Cemdisiran achieves a more sustained and complete inhibitory effect on complement activity. Cemdisiran can be used in the research of paroxysmal nocturnal hemoglobinuria and other complement-mediated diseases.
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Fitusiran sodium
0 ImagesCat. No.: HY-132587ASynonyms: ALN-AT3SC sodium; SAR439774 sodiumFitusiran (ALN-AT3SC) sodium is a siRNA strategy. Fitusiran delivers siRNA targeting the SERPINC1 gene in hepatocytes to inhibit antithrombin synthesis. Fitusiran sodium enhances thrombin activity and increases Thrombin generation, thereby restoring hemostatic function. Fitusiran sodium can be used in hemophilia-related research.
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ATF3 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS01129ATF3 Human Pre-designed siRNA Set A contains three designed siRNAs for ATF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SLC7A11 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS13325SLC7A11 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC7A11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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AS-Patisiran sodium
0 ImagesCat. No.: HY-153609AS-Patisiran sodium is an antisense strand of Patisiran. Patisiran is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran can be used for the research of hereditary TTR amyloidosis.
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NFE2L2 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS09245NFE2L2 Human Pre-designed siRNA Set A contains three designed siRNAs for NFE2L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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ZBP1 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS15958ZBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for ZBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SPP1 Mouse Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS16219SPP1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for SPP1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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IRF1 Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS06902IRF1 Human Pre-designed siRNA Set A contains three designed siRNAs for IRF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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LDHB Human Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS07572LDHB Human Pre-designed siRNA Set A contains three designed siRNAs for LDHB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
